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For anti-heal, replace ADYSSEUS BOW with TOXIC BLADE.
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Smite is an online battleground between mythical gods. Players choose from a selection of gods, join session-based arena combat and use custom powers and team tactics against other players and minions. Smite is inspired by Defense of the Ancients (DotA) but instead of being above the action, the third-person camera brings you right into the combat. And, instead of clicking a map, you use WASD to move, dodge, and fight your way through the detailed graphics of SMITE's battlegrounds.
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In general I would probably recommend going with the DT build, and you want to be flexible with the build depending on the enemy comp.
At times Trans is popular with Charybdis, and in a more teamfight mode, the CDR might be appreciated, but you'll need to determine if that's the direction you want to take.