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Smite is an online battleground between mythical gods. Players choose from a selection of gods, join session-based arena combat and use custom powers and team tactics against other players and minions. Smite is inspired by Defense of the Ancients (DotA) but instead of being above the action, the third-person camera brings you right into the combat. And, instead of clicking a map, you use WASD to move, dodge, and fight your way through the detailed graphics of SMITE's battlegrounds.
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I would generally invest less in lifesteal too. Soul Eater is fine because that allows for some ability lifesteal, but other than avoiding BF, I'd also include Crimson Claws in that.
I can see how Sekhmet's can be fun, but I'd usually go more tanky with something like Gladiator's Shield if you want an item with CDR to replace Sekhmet.