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Chronos, while great for the increased CDR, is not suggested. Typically stick with 30% CDR end build w/ Pendulum + keeping Deso.
Suggest dropping Iso, though situationally it might be okay if enemy has shields.
Other alt items to consider include Spear of the Magus (for the bonus damage and % pen, not the lifesteal), Last Gasp maybe (interesting passive power boost potential and has some health that you liked Warlock's for...). Don't know if Rod of Asclepius is viable but might be another consideration.
Blood-Soaked Shroud: I would choose a different starter. Probably either Sands or Gem, depending on what other CDR items you're considering through the rest of the build. That said, why would you choose a starter with a main component (lifesteal) that is likely going to be automatically countered because you're Aphro? The passive will be countered as well, and with only 2 damaging abilities, you're getting less out of it than other gods.
Abyssal Stone might be interesting but the effect feels a bit niche / situational in effectiveness. I won't rule it out but it's not giving you CDR or directly helping your teammates outside of potentially lessening damage in an elongated teamfight. At least you don't need to be right on the enemy god to apply it, as you can do a long distance 2 to apply the effect.
Gladiator's Shield isn't a good choice. Only 2 of your 4 abilities deal damage, and it's technically a selfish item to get a bit more damage out. Aphro's entire kit screams teammate cooperation and you could choose other items that are going to give your teammates some added benefit. I feel the choice of this item shows that her kit isn't being fully understood here.
Fae-Blessed Hoops also feels niche. Yes, the function is meant for healers, and yes it has some good general stats including CDR, but the passive is funky and has been nerfed to the point where I don't know how viable it is.
Items here that can/should be considered include Divine Ruin (for easily applied anti-heal), Shogun's Kusari later-game if your Supp doesn't pick it up for higher team DPS, Asclep again, maybe Lotus Sickle. Maybe some other Solo mains could chime in about functional items for her.
For the tank builds, Shell is good. I get the reason for Cloak, but not sure I'd get it since the healing nerfs.