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For almost every mage I build Rod of Tahuti first now that shoes are out of the game. Let me know in the comments if you'd rather it be in core or not.
Tap each threat level to view Chang'e’s threats
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1. Meditation is a noob trap relic, stop building it. It gets some use on Chang'e in SOLO over Teleport Glpyh but in no circumstances should it be built in Mid. In Mid the go-to relics for mids are Aegis Amulet and Purification Beads in 95% of cases (other 5% being Blink Rune and Magic Shell on some gods / matchups). Not only does Meditation scale poorly late (especially compared to upgraded Magic Shell ), but it is just asking for it to be countered since you're already building it on a mage healer, where most players worth their salt will build antiheal against you.
2. Your Start is impossible. You can't start tier 3 shoes + tier 1 lost artifact, you either start tier 3 shoes doing the boots rush, or you start tier 2 boots + lost artifact + a multi pot. However, I wouldn't recommend either, and since the Mage's Blessing buff a few patches ago I would in fact recommend going Mage's Blessing, Lost Artifact, 2 Mana Potions and 1 or 2 Multi Potions (or Healing Potions).
3. Warlocks isn't core. It's a pretty bad item right now, especially when unstacked. Only Baba Yaga potentially can use it fine because she stacks it quickly-ish. I would recommend Ethereal Staff instead.
4. You shouldn't need Book of Thoth for "mana issues" if you have Chronos Pendant and Mage's Blessing. Pretty underwhelming item right now, and outclassed by Doom Orb for most mages except maybe Kulkulkan and Baba Yaga.
5. Build could do with some flat pen options if you want to be damage focused.
6. I don't think Gem of Iso is worth on Chang'e, you don't have DoT abilities nor do they really control a large area.
Suggested Build:
Start: Mage's Blessing, Lost Artifact, 2 Mana Potions and 1 or 2 Multi Potions (or Healing Potions).
Build: Shoes of the Magi > Chronos' Pendant > Divine Ruin or Spear of Desolation (could just get Lotus Crown here though if you want) > Soul Reaver > Obsidian Shard > Ethereal Staff > Elixir of Speed and sell boots for Rod of Tahuti or Mantle of Discord.
Other possible build paths:
(Doom Orb Rush):
Start - Mage's Blessing, Lost Artifact, 1 Healing Potions and 2 Mana Potions.
Build - Shoes of Focus > Doom Orb > Divine Ruin or Spear of Desolation > Soul Reaver > Obsidian Shard > Rod of Tahuti / Staff of Myrddin > Elixir of Speed and Soul Gem or Mantle of Discord.
(Early Divine and Deso):
Start - Mage's Blessing, Magic Focus, 1 Healing Potion, 2 Mana Potions OR Mage's Blessing, Lost Artifact, 1 Healing Potions and 2 Mana Potions (basically you would get Lost Artifact early for this build path for MP5, and finish it later in the build into Charon's Coin).
Build - Shoes of Focus > Divine Ruin > Spear of Desolation > Soul Reaver > Charon's Coin > Rod of Tahuti / Staff of Myrddin > Elixir of Speed and Staff of Myrddin or Mantle of Discord or Ethereal Staff.
With Mid Season patch coming in a couple of weeks with new balance changes (Warlocks getting a buff), items/builds may see some shifts, although PTS Client may change some of the new item stats based on feedback, making final patch release slightly different. But my advice regarding builds will apply for until that point.
Also her 2 doesen't immune some Hard CC she is already affected by (e.g. if you were stunned before casting your 2, you can't cleanse it with your 2 while under the effect of the CC), which is another reason you need beads.
Granted, in some matchups in high level play, e.g. against a Kali jungle on enemy team, some pros have built Magic Shell for the upgraded version in place of Aegis Amulet for the block stacks, but generally it's a situational pickup, and usually you see Aegis Amulet and Purification Beads on most mids.
Some SPL examples from when Chang'e was played last year in SPL:
https://www.youtube.com/watch?v=PDBeC0XrUX0 (Game 1)
https://www.youtube.com/watch?v=hT3PSjeMJRw (Game 4)
Edit: So in summary I would say add Aegis, Beads as relic options, remove Meditation, maybe keep Blink if you want (also go Beads if you go Blink).