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Potions are up to you but I want multi pots and wards if I'm Artemis because jungles are definitely going to gank her early on. Relics is dependent but blink on Artemis is really good.
Leather Cowl
Spiked Gauntlet
Multi Potion
Ward
Purification Beads
Blink Rune
Aegis Amulet
Hunter's Cowl
Sell starter for Death's Embrace later on. Executioner can be swapped out for Fail Not if you want more attack speed. Alternatively if you want more attack speed ignore Death's Embrace and get Hunter's Cowl
Death's Embrace
Devourer's Gauntlet
Demon Blade
Qin's Sais
Fail-Not
Deathbringer
Hunter's Cowl
The Executioner
Shadowsteel Shuriken
Ichaival
Hunter's Cowl
Devourer's Gauntlet
The Executioner
Qin's Sais
Atalanta's Bow
Dominance
Purification Beads
Aegis Amulet
Blink Rune
Demon Blade
Toxic Blade
This build is still in experimental phase. Death's Temper takes a while to get online but at level 20 the Silverbranch stacks will create juicy fat auto attacks. Ody Bow is a possible option late if you want it but the damage output on single targets will suffer.
Death's Temper
Devourer's Gauntlet
Ichaival
Asi
Silverbranch Bow
Atalanta's Bow
Y
B
A
X
Tap each threat level to view Artemis’s threats
Tap each synergy level to view Artemis’s synergies
Hi! Thanks for clicking. This was my first build and I'm excited to return to Smite to find out my main squeeze Artemis went from C tier trash to S+ broken tier ADC! She's not as broken anymore with the updates but all the buffs she's received has finally made her into a very popular, powerful ADC choice in the meta. xZeroStrike has an excellent in-depth guide already out there which helped me out a lot. I'm just going over builds and I'm not sure why this got tagged as "in-depth guide" but I'm a build junkie. If you'd like to read his guide to learn Artemis and how to play her you can check it out here: A much better Guide on Artemis than I could ever make. So let's talk about my favorite hunter.
Are you tired of missing your wall bounces on 
Hou Yi? Are you tired of missing your axes on 
Ullr? Are you tired of missing your snipes with 
Rama? Do you hate when people beads your ultimate as 
Heimdallr? Are you tired of playing 
Cupid... because he's Cupid. Well ladies and gentlemen do I have the solution for you! Introducing:
Calydonian Boar is a stun you literally can't miss with. It hits multiple people within the radius. Her traps Transgressor's Fate will make your enemies feel like Sideshow Bob stepping on a dozen rakes. With the recent buff her trap are now on much faster cooldowns meaning you can spam them till your heart's content. She has one the best passives for hunters and attack speed/movement speed buff with Vengeful Assault only adds to her overwhelming attack speed. And finally her AoE Suppress The Insolent has a nice width to it while doing decent damage. Calydonian Boar might honestly be the best ultimate in any hunter's arsenal. The boar will target a cone like area in front of you line of you stunning them while doing decent damage, then chases down anyone else in circle radius with good range one by one. With some items in you bag you can run from one squishy to the next killing them off as Miss Piggy does her thing. This really is in my opinion the best hunter ultimate in the game and the entire reason to pick her. The stun is really unique as well where it doesn't stun all your enemies at once in an AoE, no instead it stuns enemies one by one with a small pause in between. Why is that good? Because with a full build you could easily kill a squishy in the time they're stunned and then target the next person the Boar stuns after. It's like having a personal support CC enemies for you one by one to get easy kills. This ultimate is built for triple kills. Shadowsteel Shuriken actually feels a lot better than Toxic Blade if you're doing a crit build. The movement speed on Toxic Blade is nice and I still find myself building it if I need that but Shadowsteel's stats on top of high crit chance builds makes it a great choice. With these builds you're pretty much guaranteed to get a crit almost every auto and one crit applies the full anti heal.
Building to take down squishy targets isn't much of a thought process. Get some attack speed, get some power and a lot of crit. The item I think is really the main attraction is Blink Rune. Nothing wrong with picking up Aegis Amulet instead especially if you feel the game is close and don't want to play too risky. However Blink just feels so good on Artemis given her lack of dash, leap or any mobility. I found many times I missed an easy kill due to them having some sort of chase option and even with 
Heavenly Wings was not able to catch up. Blink gives you the ability to play like an Assassin.
Use blink to flank a teamfight from behind a wall and pick off anyone out of position or too far from their team. Blinking into someone running around in jungle and letting your Calydonian Boar go to work on them. Blink to catch up to someone running away from you. Or to use it to avoid dying. Blink gives you the element of surprise and get in close enough so that beads aren't going to help them. Just be sure to let your team know you're blinking into a team fight to pick off carries so after you kill them they can help you get out alive. But the best way to live if just killing everyone. So here's the bread and butter Miss Piggy combo.
Combo
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I tend to save Suppress The Insolent for the finishing move as they'll most likely beads the ultimate but if you blinked behind them you'll hit enough autos to get their health down enough to kill with your Suppress The Insolent. The real trick to this combo is using Transgressor's Fate effectively. If you know their beads is down then Blink in and use your trap first before starting your combo placing it slightly behind them. If you think they still have beads place the trap far enough behind them so they won't be CC immune and they'll be forced to move around it or hopefully just run into it. You can also use it to cut off an escape route. I see a lot of Artemis players using the traps ineffectively which can make or break an Artemis. This ability adds a layer of chess like strategy to her complexity. Knowing where your enemies will move and how to use the trap effectively takes some planning.
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Death's Embrace
When it comes to the debate for Hunter's Cowl vs Death's Embrace I think it comes down to preference. The lifesteal and attack speed from Cowl are extremely valuable especially for someone like Artemis. But the reason I tend to sell for Death's Embrace more often is simply for the massive power spike in damage. The passive will also provide very good lifsteal as well as mana stealing which is great to have for someone who spams traps and speed abilities.Fail-Not
The Fail-Not isn't seen too often anymore. I don't care. This is my favorite item on Artemis. She has the best ultimate for ADC's in the game. Any item that provides cooldown is extremely valuable. It also provides pen, power and crit so it still fits well into this build.Wind DemonWind Demon The Wind Demon is the go to crit item for any build. I swear Hi-Rez is lying about the crit chance with this thing. This item alone provides a massive amount of crit chance that the game is hiding away in the coding. This item is a staple as the passive allows you to shmoove and carve through armor. As for Qin's Deathbringer and Devour these are all staple ADC items for sustain, crit damage and dealing with high health enemies. Beads are your lifeline. Never engage too deep into a fight without beads. I'd recommend upgrading it before you even finish stacks on Devo. Should you get stunned your ability to sustain with lifesteal goes out the window and you'll be easily killed. With the amount of crit you'll get from all 3 items you'll proc Wind Demon easily adding a lot of great benefits to your stats.  Rage is pretty niche since Wind Demon provides so much crit chance, plus you'd have to leave out something like Deathbringer although any crit build without that item is just losing out on massive damage. Yes this build does lack in attack speed. However your 2 ability will provide you attack speed. This is a build that's better suited to people who are good at hitting autos, which will hit like a mack-truck at full build since crit runs off your passive due to the ultimate and trap CCs that adds bonus damage to targets WHICH is your ultimate so that will proc Fail-Not to make sure every hit is a crit! Damage on top of damage on top of damage with this build.
Item Counters: If you see tanks getting  Spectral Armor that's when you should switch up your build. Crit will still work well against squishy targets but mix up some crit items for more beefy damage. Instead of Fail-Not you can get Dominance, switch Wind Demon with The Executioner and lastly Deathbringer can be replaced with Ichaival or even Atalanta's Bow. Basically just switch to the attack speed build.
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Why bully tanks?
ADC's act real tough when their supports are leading the fight. You take them out and now you have a scared squishy ADC running for the tower. I like building heavy pen% for ADC's mainly because you're always dealing with tanks. Solo players love diving squishy targets and supports are annoying constantly peeling you off easy kills. You take them out of the picture and now you're free to do whatever you want to the enemy team. Your mid lane mage, solo laner and jungler will have no problem dealing with squishy targets so I always felt like ADC's should focus on the role of dealing with tanks. Hunters can melt tanks way faster than any other role so why not make that your primary job?
Optional KEEP YOU ALIVE ITEMS!
Don't always ignore the defensive items especially for Artemis. Consider these options if you're getting dived a lot or need some some help escaping situations.
Mantle of Discord
Don't always sell boots for more power. I used to make the mistake of ignoring defensive items cause I was a power addict. 
Mantle of Discord is a fantastic item that can help you out massively later in the game. If you're getting dived and peeled you need this item. The stun AoE will ensure you can stop the pressure and either escape or start hitting them back to regain your health if you have your Devourer's Gauntlet stacked up. Even if you need it as a 6th item, you can sell boots for something else. 
Magi's Cloak is also pretty good but it's an item that really benefits gods with some sort of escape. However Magi's Cloak does show up in my Crit build pretty often just so I can kill squishy targets without error.
While Mantle of Discord is my preferred item for defense Magi's Cloak can be pretty useful for the health and free beads if you're picking off squishy carries. The last thing you want is to get CCed the second you blink in to hit someone and die immediately. Especially late game while you're trying to pick someone off running around, there's are so many builds designed to one-shot. This item will make sure when you blink in you'll get your combo off. It's happen to me a few times where I flank in an area where I don't think there's a Ward but sadly there is. They have their CC ready and aimed at my route then I walk right into it. Magi's Cloak will save you from that embarrassment.
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I feel like there's some really amazing Silverbranch build that can be done on Artemis in ranked games. With these new starter items they can add insane attack speed numbers. For Artemis and her buff this means Silverbranch will do massive damage for her. I just don't feel comfortable building it in ranked just yet cause I can't find the right build stacking item on her.
This build however almost reach power cap once you active your 2. It has decent pen to deal with tanks. It's just a little lackluster compared to heavy damage power items though.
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Eagle Eye
Ring of Hecate
Maybe try out 2
I wouldn't build
I don't like telling people what they need to put in their build, however, you really should add
For what I assume is the build against a dominantly squishy team,
Where you talk about counters to crit, you turn your build around into a power/pen build which is good. For clarity maybe make a build out of it along with Tank Buster and Carry Slayer. Also I would not purchase
For the combo personally I would ult as soon as I blink in. Blinking and using 2 abilities before your ult gives people time to react and prepare to use their beads or jump away before you even ult.
Overall though, great concept and I can see you put a lot of time and effort into it fantastic write up for someones first build in fact I would say it's better than a lot of mine lol. I'll upvote once you work
Getting Mana over Multi means I just pop Mana when I need it. In some cases when I've gotten Multi, I'm in a situation where I need Health OR Mana but not both, and so part of it goes to waste.
That said, usually I opt for 3 healing and 1 mana, rather than 2 and 2. But if I'm able to consistently be aggressive (usually with a good Supp), then I find myself using up more mana and wish I'd gone 2 and 2.
Regarding Qin's + Crit, I have a writeup for that at the bottom of this chapter of the items guide. Main gists: 1) Qin's passive doesn't increase in damage due to crits, 2) crits don't directly benefit from Qin's passive, and 3) crits typically focus a bit more on power (since crits scale 2x or more based on power from items), while Qin's typically wants high base AS. Most builds don't do both, though there are more opportunities to do so with the current item options for hunters. At this point, I think early crits with a very late Qin's can be fine, as long as you've got the main/core items covered.
All of your other points (no Asi after DB, Ata as core, etc.) are solid.
@S7evin424, I typically wouldn't consider
My general build direction would be one of two ways, both being probably pretty meta at this point. I'd go Devo's Ninja Rage Ata DB+WD (whichever order) and replace Ninja with a situational item in a crit build. I'd go Devo's Ninja Ata Qin's Silver w/ 2 situational items in a Qin's based build. Strong preference for crit at this point though.
You don't really have to make a "tank killer" build anymore, because it's very easy to get 30+% penetration. Obviously Qin's is more helpful against tanks than squishies, but even then, you'll deal a ton of damage no matter what.
And while you have a point that having both Devo's + Asi in the same build can help make up for errors in play due to the high lifesteal, back to back lifesteal isn't suggested. Getting Asi at that point is delaying other items that are likely going to be more helpful at that stage of the game. Keep in mind also. Rage 3rd helps get stacks earlier. Ata 3rd can help with tower/objective damage moreso than Asi.
The reason tank buster ends up being my favorite build is mainly because a team will already have a lot of roles that can deal with squishy targets. Solo, Jungle and Mid are typically going to be able to deal with a backline. In my experience tanks end up being the main source of problems during teamfights. Having one damage role focus down high sustain/tank gods so they can't get in the way of your other teammates from doing their job just feels like it gives everyone some breathing room. It entirely depends on the tank, if it's a healing/support tank that doesn't have many CC or isn't good at damage or anything like where it's not a threat exactly, then tank buster isn't needed. But if it's a good damage, CC tank that can easily peel off your teammates or cause some serious problems in fights getting them out the picture early can be really helpful. Mainly because the tank is going to have to focus on buying counter items just to deal with you, if you can make a tank replace items in their build just to deal with you then tank buster has done it's job because that's one less damage item, that might be one less helpful aura item or so on.
The tank buster is entirely situational. The whole reason I made it was because we kept running into this Ares main that was demolishing us in ranked. Kept getting queued up against him all day. Could not do anything to him or his team cause he wouldn't let us. I just said screw it and said I'd build a full anti-tank build the next time we ran into him. I was able to take him out early in team fights then we finally won a game against him. Been using it ever since when I see troublesome hard hitting tanks.
As for the
If we were talking about Artemis before they fixed her ult yeah it wouldn't be worth it cause her ultimate was weak since Miss Piggy went off doing whatever she wanted, or sometimes not doing anything.
If you don't like the Fail-Not though I'd swap it out for
And about the Asi early. I really suck at Artemis in early game. Some people are good enough to get around it but I just feel with her lack of escape taking damage and getting peeled is going to happen. I prefer to have the extra lifesteal while building Devo stacks. Since she's a late game hunter I completely focus on just staying alive while I farm. Asi kinda helps me in that regard. After you getting Devo stacks though you'll be healing for nearly 200+ HP a hit. That's some juicy lifesteal and makes me feel more confident.
It isn't core but it's certainly a good mid to late game option for her.
@S7evin, rather than
Thanks for the feedback!
Atalanta's bow should be one of your core items and hence built around the 3-4 slot, maybe 5th depending on what you're building. There are definitely more choices for a late game item, especially in a crit build.
These days, I'd only consider O-Bow in a non-crit build (crits again want power), and I'd probably only ever build it when Silver is in the build, especially for a god like Art with high AS steroid.
Also never get Warrior Tabi on Artemis anymore, even in Qins builds.
Executioner sucks *** unless you’re an AA hunter like Artemis in a team of 4+ physicals and want to help your team shred frontliners.